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Plant-based dietary supplements: How can a brand secure and enhance its offering?

With nearly half of dietary supplements containing plant-based ingredients, the French nutraceutical market is striving to meet consumers’ increasing demand for naturalness. However, this successful trend is accompanied by certain pitfalls: issues of adulterating plant material are indeed common in the dietary supplement sector, despite existing regulatory frameworks and controls.

Many brands therefore understand the interest and importance of differentiating themselves by capitalising on the effectiveness and safety of using such products. Some supply chain stakeholders are even spearheading a new activism movement: providing more guarantees and transparency to consumers with a logo on the finished products, endorsing their quality and safety.

Perception of dietary supplements: between enthusiasm and crisis of confidence

It is no longer to be demonstrated that the dietary supplement market has been booming for several decades – the latest figures still indicate an 8% growth on the French officinal network in 20231 – and is driving numerous innovations (let’s take the example of “sensory” galenics, to which we have dedicated a complete article here2). According to a study by Harris Interactive Toluna3, 59% of the French reported consuming dietary supplements between 2020 and 2022. Paradoxically, the overall perception of this product category remains mixed, particularly among non-consumers: “Unclear“, “misleading“, “useless“, and “dangerous” are words frequently used to describe  the image that the French have of them4 expressing scepticism about the safety and the effectiveness of dietary supplements.

Enthusiasts of nutraceutical solutions lament a lack of proof of efficacy with their average satisfaction rating being 6.9/10. On the other hand, a lack of trust is frequently mentioned among non-consumers who feel the need for scientific and medical endorsement5.

the difficult choice of plant-based dietary supplements for consumers

Risks associated with the quality of plant ingredients

One may question people’s distrust. “Dietary supplements: how to decipher the real from the fake? – What are dietary supplements worth? – Are dietary supplements really effective? – Plant-based dietary supplements: health risks – Ineffective or even dangerous.6

Dietary supplements are regularly scrutinised and criticised in the press, raising questions that are equally important as they concern their safety. For those products composed of plants, the central issue revolves around the “real” nature and quality of the plant-based ingredients used.

These can be subject to risks of adulteration, i.e., any practice aimed at deliberately altering, modifying, or contaminating plant-derived products in order to deceive consumers or gain an illegitimate economic advantage.

This alteration can take various forms, such as the addition of foreign substances, dilution, or substituting lower-quality ingredients.

Each of these biases results in an inevitable gap between what is claimed on the labelling of the finished product and its real composition, which can deceive a consumer who has little choice but to “believe what is written.”

Note that unintentional mix-ups or accidental contaminations can also compromise the quality of a plant material and its derived ingredients.

Adulteration or the art of substitution

For example, elderberries (Sambucus nigra) became particularly coveted for their immune properties during the COVID pandemic. The American Botanical Adulteration Prevention Program (BAPP) issued an alert in 2021 revealing that out of 694 samples of elderberry-based products analysed, 119 (17.1%) were adulterated7. The falsification of these preparations frequently involved the addition of undeclared extracts of black rice (Oryza sativa), considerably cheaper than authentic elderberry extracts, as well as substitutions involving other plant extracts rich in anthocyanins and blue or purple food colourings…

From peanut husks masquerading as grape seeds to Japanese pagoda trees pretending to be Ginkgo biloba, all tricks are good to deceive phytochemical analysis devices – which are often not discriminating enough – and make substantial savings by opting for cheaper substitute plants. This results in a degradation of the effectiveness and safety of the concerned finished products.

Dilute to better dominate

In France, the DGCCRF conducted a surveillance survey in 2017 on plant-based dietary supplements available on the French market8. Monitoring focused on the composition and levels of active ingredients in the analysed products. The results revealed a non-compliance rate of 17%, mainly due to discrepancies between the quantities indicated on the labelling and the measured levels.

Perhaps the most frequent but also the most insidious falsification is that the claimed plant is indeed present in the finished product but in quantities too low to expect to achieve the effectiveness promised by the brand and expected by the consumer. According to BotaniCERT, a plant analysis laboratory and plant expert, 47% of plant-based ingredients analysed between 2020 and 2021 were “diluted or highly diluted.” 9

Transparency, effectiveness, and safety: a triple challenge for plant-based product brands

Consumer  demand for transparency is increasingly leading brands to have their products tested or certified by third parties, accredited independent laboratories. For marketers, the challenge is significant: to persuade consumers to choose “value” over price and find a reliable way to guarantee them effectiveness and safety. In 2022, Lisa Thomas, then Marketing and Innovation Director at Herbalife Nutrition, stated: “Third-party certification is an additional level of security offered to consumers. Although our company conducts rigorous audits of our facilities and product testing, there are certain areas where consumers want additional guarantees.”10

The approach, already widespread in the United States, is increasingly being adopted in Europe and notably in France with the recent launch of the first European quality brand for plant-based products.

transparency effectiveness and safety for dietary supplements for an happy consumer

The Botani+ quality brand just recently launched, already adopted

Created in 2023 by BotaniCERT, a French laboratory expert in the monitoring of plant raw materials, the Botani+ brand aims to guarantee consumers safe and effective products.11

Concretely speaking, obtaining the Botani+ brand results in putting a logo on the award-winning finished products.

This easily identifiable logo allows consumers to navigate through a wide and sometimes difficult-to-decipher range of offerings. It is proof that the product in question has successfully passed a series of chromatographic analyses, advanced techniques that allow the separation, identification, and quantification of the chemical components present in plant extracts.

Botani+ approved botanical quality

Phytochemical identification notably ensures that:

  • The plant is indeed the one claimed on the product labelling as well as the part used (leaf, root, etc.)
  • The plant is not mixed with other species
  • The material is not enriched with synthetic or natural molecules
  • Plant actives are present in sufficient quantities to unequivocally authenticate the species present

Dosing the actives ensures that the plant is not excessively diluted and that its concentration is sufficient to ensure the presence of physiological effects in the finished product.

Reassuring for consumers, the Botani+ logo is also a choice indicator for brands wishing to communicate on the rigor and seriousness of their quality approach. VIT’ALL+ and Nonna Lab12,13  were the first ambassadors of this new movement, providing even more transparency and quality in the plant-based dietary supplement market.

As a brand, sparking an initial purchase is one thing, ensuring it is purchased again is another issue. This depends on the satisfaction initially felt by the consumer, which will encourage them to come back to the same product. Effectiveness is essential because it guarantees the market longevity of the product. This is based on the choice of the formula and at least as much on the selection of ingredients.

Do you want to stand out among your consumers and highlight the quality of your range of plant-based products? BOTANI BRANDS is your trusted partner to assist you in launching Botani+ validated products, synonymous with quality, safety, and effectiveness. By combining the skills of our various experts, we are ready to efficiently and effectively orchestrate the development of your plant-based health product. Whether your brief is finalised or still in the consolidation phase, we are here to build on your project and deliver a turnkey solution.

Contact us to discuss your project

Sources:

  1. GERS data 2023
  2. Galenic innovation: the importance of combining effectiveness and pleasure in food supplements – BOTANI BRANDS Article (https://www.botanibrands.com/le-blog/)
  3. 2022 Barometer of Dietary Supplement Consumption in France (https://www.synadiet.org/app/uploads/2022/04/202111060_harris_interactive_rapport_barometre_conso_cpal_2022_v2.pdf)
  4. Challenges and Opportunities of Dietary Supplements by Harris Interactive Toluna for NFBD 2019 (https://harris-interactive.fr/catalogue/pages/complements_alimentaires.html)
  5. Statistics corresponding to the question: “On a scale of 1 to 10, are you satisfied with having taken/taking food supplements?”
  6. Headlines about Dietary Supplements
  7. BAPP – Botanical Adulterants Prevention Program – Case of Elderberry Adulteration (https://www.herbalgram.org/resources/botanical-adulterants-prevention-program/adulterants-bulletins/european-elder-berry-and-berry-extracts-bulletin-june-2023/)
  8. Report of the National Academy of Pharmacy “Dietary Supplements Containing Plants” (https://www.theragora.fr/revues/ANP-rapport-compl%C3%A9ment-alimentaire-0219.pdf)
  9. Botanicert – Case of Plant-based Ingredient Falsification – Internal Statistics 2020-2021 (https://www.botanicert.com/actualites/)
  10. Herbalife – Certification by Independent Laboratory (https://www.nutraceuticalsworld.com/contents/view_online-exclusives/2022-05-10/third-party-certifications-support-consumer-demand-for-quality-and-transparency/)
  11. Botani+ First Quality Brand for Plant-based Products (https://www.botaniplus.com/)
  12. VIT’ALL+ validated by Botani+ (https://www.vitalplus.com/)
  13. Nonna Lab validated by Botani+ (https://nonnalab.com/collections/nonna-choc)

Galenic innovation: the importance of combining effectiveness and pleasure in food supplements

Galenic pertains to the presentation of a product and how its ingredients are formulated. Its main objective is to optimise the effectiveness of the formula by promoting optimal absorption of its compounds of interest. But it doesn’t stop there… The food supplement market has what it takes to reimagine galenic formulations in more sensory and appealing forms. Beyond a quest for innovation, the goal is to enhance the consumer’s experience and encourage them to complete their treatment. Let’s delve into these formulations that provide a boost to adhering to the treatment.

Galenic formulations for effective results

Galenic formulation takes its name from Claude Galien, the father of modern medicine and pharmacology1. It focuses on the properties of the key active ingredients in a formula, their dosage, and the most suitable way to administer them to ensure effective absorption in the body.

Dynamic and competitive, the food supplement market seems eager to embrace galenic formulation as a differentiation vector. Notably, 63% of French consumers state that the product format is a decisive factor in their purchasing decisions, according to the latest Synadiet observatory survey conducted in 20232.

Optimised release for enhanced bioavailability

The effectiveness of a finished product is based on the proper absorption of its active compounds. Whether they are water-soluble, fat-soluble, sensitive, in powder form, living or inert, the ingredients of a formula may have characteristics that require careful consideration of the appropriate galenic approach.

For instance, consider a sublingual spray recently developed by an Italian developer. Its patented nano-emulsion technology enables the solubilisation of lipophilic molecules insoluble in aqueous solutions, thereby improving the bioavailability of otherwise challenging-to-absorb molecules.

Fat-soluble vitamins A, D, K, and E are excellent candidates for such a process. Not to mention, key ingredients in successful categories, such as melatonin for sleep or coenzyme Q10 for IN-Out beauty (evaluated as a “high-growth” category with +5.1% growth posted between 2018 and 2023, according to a study on 2024 marketing trends3).

Some CDMOs also offer three-layer tablets, an innovative galenic approach that enhances product performance. By layering ingredients through successive compression, this format allows the separation of incompatible compounds and their controlled release at different locations in the gastrointestinal tract.

Acacia gum, a perfectly suited excipient for buccal administration

Some excipients also play an important role in the action and effectiveness of a formula. One can think of acacia gum (we have dedicated a complete article to it here4). This resin extracted from the Acacia senegal (L.) Willd. tree is not only a fibre with multiple nutritional properties but also a gelling agent perfectly suited for galenic forms like “suck gums.”

Its melting texture allows the gum to stay in the mouth for an extended period, thereby enabling the continuous diffusion of active ingredients into the buccal mucosa5.

Used for a long time in the pharmaceutical industry (an iconic example being the Euphon throat lozenger6), acacia gum is now making its way into the dietary supplement market.

For example, Cooper Laboratories turned to this natural texturiser for its product Collugomme Gorge irritée, launched in 20237. The acacia gum, also known as gum arabic, in Collugomme lozengers promotes the release of essential oils from eucalyptus and peppermint, forming a protective film that relieves irritated throats.

Lehning Laboratories also opted for acacia gum as an excipient for their “Pâtes suisses,” a range of nine sugar-free gummies, including one with vitamin D3, known for its lipophilic nature. The slow dissolution of these acacia gum-based lozenges is particularly advantageous for liposoluble compounds, as studies have shown that the more lipophilic a molecule is, the higher its transbuccal penetration capacity (Beckett and Moffat, 1971, 1969, 1968,9,10).

Galenic formulations for enhanced consumption pleasure

Breaking away from “pharmaceutical codes” marks a turning point for many players in the food supplement sector, leading to the emergence of fun, enjoyable, and even gourmet galenic forms. The goal is clear: make the consumption of food supplements more enjoyable to improve adherence and, consequently, support the effectiveness of the treatment (and ultimately, repeat purchasing).

The “pleasure” promise: a primary axis of food innovation

The World Food Innovation Barometer, a study conducted in 2023 by the Protéines XTC consultancy firm, reveals that pleasure remains the main driver of innovation with the potential to meet consumer expectations11. These expectations are segmented by XTC along five axes: pleasure, health, ethics, form, and practicality. The pleasure axis includes “variety of senses,” “sophistication,” “exoticism,” and “fun.” This is an undeniable source of inspiration for the nutraceutical sector, strengthening its ties with the food market by paying more attention to the “sensoriality” of its solutions.

Stimulating senses and curiosity

Making the consumption experience enjoyable with a hint of “come back for more” is the challenge to meet. Food supplements increasingly allows itself to appeal to consumer’s senses.

Starting with sight: many galenic innovations carefully take care of their physical appearance – consider, for example, UPSA x Nourished gummies – which stand out with their multi-coloured layers, each corresponding to a specific ingredient12.

Some developers are even beginning to explore the sense of smell, a crucial parameter in emotional perception and product memorisation, well-known mechanisms in the world of perfume. In line with this, a CDMO plans to launch scented capsules in 2024.

Some ingredient suppliers also exploit this olfactory and sensory dimension. For example, in 2022, an anti-stress active ingredient was launched, using the retro-nasal route to act on brain areas involved in managing emotions.

More specifically, hearing can also contribute to enhancing the consumer experience. Pullmoll’s “Les Bienveillants” claim to provide an “enhanced experience” with free audio sophrology exercises offered with the purchase of a box of Relaxation gummies.13

Taste above all

Unsurprisingly, taste remains the most worked-on sense to transform a food supplements treatment into a gustatory and nutritional experience. Young brands like Nonna Lab have embraced the relatively underexplored idea in Europe but already well-established in the United States14: “combining pleasure and health” by offering nutraceutical ingredients in a food matrix. Nonna Lab, presenting itself as a Foodceutic laboratory, opted for a chocolate ball, justifying that “the French consume an average of 7 kg of chocolate per year,” and “one out of every two people does not complete their food supplements treatment.”15

In the United States, a company has developed a patented freeze drying  technology that allows it to offer a “100% fruit delivery system”, a galenic form composed solely of freeze dried fruit purees to which nutraceutical ingredients can be added (without risking alteration). The experience aims to be both tastefully enjoyable and clean-label: these fruit bites contain no added sugar or flavour, colouring, and are almost calorie-free (except for those naturally present in the fruits).

Nutrition, quality, and safety: indispensable pillars

Galenic innovation in nutraceuticals sometimes comes at the expense of the nutritional and qualitative aspects of the formulations. Hence, it is crucial for these stakeholders to demonstrate that the novelty of their solutions does not compromise their quality.

Chocolate pearls from Nonna Lab are Botani+ validated, an approved botanical quality trademark.

For instance, the chocolate pearls from Nonna Lab are Botani+ validated, a quality brand that assures consumers that the formulas are safe and effective (with plant-based ingredients having successfully passed a set of phytochemical controls)16.

Discover Botani+. An approved botanical quality trademark.

Embark your consumers on an unforgettable sensory journey! BOTANI BRANDS puts its expertise at your service through a team of experienced experts, specialised in natural ingredients and product development. From defining the formula to creating a distinctive galenic form, we can manage your project from A to Z.

Our goal is clear: to build a solution that offers a unique consumer experience, with no compromises on quality or formula effectiveness.

Many brands have already trusted BOTANI BRANDS in their quest for galenic and sensory innovation. To benefit from our expertise, feel free to contact us!

Trust us and get in touch to discuss your project

“It is always necessary to know the limits of what is possible. Not to stop, but to attempt the impossible under the best conditions.”

Romain Gary

Sources:

  1. Galien, Galen, the true father of medicine – Véronique Boudon https://www.lhistoire.fr/galien-le-vrai-p%C3%A8re-de-la-m%C3%A9decine
  2. 2023 Barometer of dietary supplement consumption in France – Toluna Harris Interactive https://www.synadiet.org/app/uploads/2023/04/Observatoire-2023.pdf
  3. Nutraceutical market trends for 2024insights by PharmaLinea & IQVIA
  4. Acacia Gum and Gummies: The Story of a Beautiful Encounter https://www.botanibrands.com/en/acacia-gum-and-gummies-the-story-of-a-beautiful-encounter/
  5. Medication Absorption – Oral Administration https://www.msdmanuals.com/fr/professional/pharmacologie-clinique/pharmacocin%C3%A9tique/absorption-des-m%C3%A9dicament
  6. Euphon medication based on acacia gum https://www.vidal.fr/medicaments/gammes/euphon-3520.html
  7. Collugomme from Laboratoire Cooper – acacia gum lozenges for sore throat https://www.boticinal.com/cooper-collugomme-gorge-irritee-30-gommes.html
  8. Beckett, A.H., Moffat, A.C., 1968. The influence of alkyl substitution in acids on their performance in the buccal absorption test. J. Pharm. Pharmacol. 20, Suppl:239S+.
  9. Beckett, A.H., Moffat, A.C., 1969. Correlation of partition coefficients in n-heptane-aqueous systems with buccal absorption data for a series of amines and acids. J. Pharm. Pharmacol. 21, Suppl:144S+.
  10. Beckett, A.H., Moffat, A.C., 1971. The buccal absorption of some barbiturates. J. Pharm. Pharmacol. 23, 15–18
  11. 2023 global food innovation barometer – https://www.proteinesxtc.com/barometre-de-linnovation-alimentaire-mondiale/
  12. UPSA x Nourished – 7 layers of well-being https://upsa-nourished.fr/
  13. Auditory stimulation with free sophrology audio exercises by Pulmoll https://bienveillants-pulmoll.com/
  14. Market Study by Botani Brands – food and nutraceuticals: at the intersection of two worlds
  15. Chocolate pearls Nonna Choc from Nonna Lab https://nonnalab.com/collections/nonna-choc
  16. Botani+, Quality brand for plant-based products https://www.botaniplus.com/en/

Our references

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